2 edition of References on naturally occurring neoplasms in animals. found in the catalog.
References on naturally occurring neoplasms in animals.
Medical Museum (Armed Forces Institute of Pathology). Registry of Veterinary Pathology.
Written in English
|Statement||Compiled by F. R. Robinson, R. J. Brown [and] H. W. Casey. Edited by Sandra Rozof.|
|Contributions||Robinson, F. R., comp., Brown, Richard J., joint comp., Casey, H. W., joint comp., Rozof, Sandra, ed.|
|The Physical Object|
|Pagination||viii, 125 p.|
|Number of Pages||125|
Summary In the 10 years to November , 33 different types of naturally occurring neoplasms were diagnosed in domestic fowls submitted for necropsy examination. The most prevalent type was lymphoma (/ = 80%) including two cases in chickens from a flock free from Marek's disease virus, exogenous avian leukosis viruses and reticuloen‐dotheliosis virus; the Cited by: Jcmllldd J J AND PIIOII:il]I:IIK~ Journal of Photochemistry and Photobiology n,~ B: Biology 27 () ELSEVIER News and Views Variation in the distribution of a phthalocyaCited by: 8.
Immunological aspects of mammary tumors in dogs and cats: a survey including own studies and pertinent literature. Vet. Immunol. Immunopathol., Naturally occurring cancer in companion animals parallels cancer in man more closely than does experimentally induced cancer in inbred laboratory by: The use of naturally occurring cancer in domestic animals for research into human cancer: general considerations and a review of canine skeletal osteosarcoma. Brodey RS. For many years, research into human cancer has concentrated on human patients and on artificially induced neoplasms Cited by:
Further support for the hypothesis that low-dose-rate exposures can lead to elevated mutation rates comes from a recent meta-analysis of the effects of naturally occurring radioactive materials on plant and animal populations around the world (Møller and Mousseau b). This study surveyed the results from more than publications to Cited by: The Role of Clinical Studies for Pets with Naturally Occurring Tumors in Translational Cancer Research: the study of naturally developing cancers in animals as models for human disease - as one way to improve cancer drug development and reduce attrition of investigational agents. Show this book's table of contents.
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References on naturally occurring neoplasms in animals Author: Farrel R Robinson ; Richard J Brown ; Harold W Casey ; Sandra Rozof ; New York Academy of Medicine, ; All authors. Spontaneously or naturally occurring tumors in domestic animals are of particular interest for comparative studies - these tumors occur in heterogenous outbred populations of animal closely sharing man's environment; their cause is generally unknown; many tumors occur in numbers suitable for detailed investigations; and tumors generally occur in aged animals, thus facilitating study of.
The neoplasms were identified, often after consultation with texts describing neoplasms in domestic fowl (Campbell, ), humans (Ashley, ) and/or other domestic animals (Jubb et al., ), and were classified according to a histiogenic system.
RESULTS The incidences of naturally occurring neoplasms in the various avian species are given in. Spontaneously or naturally occurring neoplasms in domestic animals are of particular interest for comparative etiological studies. Usually, they are observed in aged animals with chronic diseases, often associated with natural neoplasia, and can derive from natural exposure to several physical, chemical, and biological factors.
REFERENCES - The Role of Clinical Studies for Pets with Naturally Occurring Tumors in Translational Cancer Research Your browsing activity is empty. Activity recording is turned off. Naturally occurring glycerolipids containing ether bonds can be classified according to two structural types: alkyl (I), and aikenyl (II).
Ether-Linked Lipids in Neoplasms of Man and Animals: Methods of Measurement and the Occurrence and Nature of the Alkyl and AlkEnyl Moieties | SpringerLinkCited by: 8. Some observations on naturally occurring neoplasms of domestic fowls in the State of Victoria, Australia () R. REECE1 Department of Agriculture and Rural Affairs, Veterinary Research Institute,2 Parkville, VictoriaAustralia SUMMARY In the 10 years to November33 different types of naturally occurring neoplasms.
Forty‐five types of naturally occurring neoplasms ( cases) were identified in 69 avian species (excluding domestic fowl), belonging to 25 Families from 13 Orders. The most prevalent tumours were lymphomas (63 cases in 25 species), fibromas and fibrosarcomas (62 cases in 15 species), and lipomas and liposarcomas (56 cases in 16 species).Cited by: This report gives the rationale, criteria, and guidelines used by the NTP for combining neoplasms for the evaluation of long-term rodent toxicology and carcinogenesis studies.
The guidelines are based mainly on lesions occurring in the F/N inbred rat and (C57BL/6 x C3H)F 1 mouse and may or may not be appropriate for other strains or by: The development of naturally occurring lung tumors is related to aging.
In rats, mice, and hamsters younger than 12 months naturally occurring pulmonary tumors are exceedingly rare. The majority of them are found in animals older than 20 by: 4.
Traditional preclinical mouse models of cancer have been very useful for studying the biology of cancer, however they often lack key characteristics of human cancers.
As a result, many novel drug candidates fail in human clinical trials despite evidence of drug efficacy in those preclinical models. Thus, researchers are seeking new approaches to augment preclinical knowledge before undertaking. Although inhalation is the primary route of exposure in experimental studies, in the past, many studies used intratracheal instillation or direct injection of known carcinogens into the lung.
These experiments often resulted in the development of squamous cell carcinomas even though they are very rare as a naturally occurring neoplasm. Many of these concerns may be allayed through the study of naturally occurring tumors in our companion animal population, (i.e., dog and cat pet population).
Companion animals with naturally occurring tumors, although presently underutilized, have and should continue to provide an excellent opportunity to investigate many aspects of malignancy Cited by: Following a short historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the handling and housing of animals.
It then goes on to describe the animal models available for different cancer types, from natural cancer models in mice and dogs to humanized animals.
Whitfield P, Noble PJ, Major H, et al: Metabolomics as a diagnostic tool for hepatology: validation in a naturally occurring canine model. MetabolomicsWilkins MR, Sanchez JC, Gooley AA, et al: Progress with proteome projects: why all proteins expressed by a.
Cancer, however, affects a great variety of mammals, particularly those that have been domesticated. Suchf naturally occurring neoplasms are common in dogs, cats, cattle, horses, etc., and offer fertile ground for studies relating to epidemiologyf, etiology, immunobiology, and therapy.
Canine osteosarcoma is described in detail. Common neoplasms in animals – an overview Article in Journal of Animal Research 2(2) January with 32 Reads How we measure 'reads'. Many of these concerns could be allayed through the study of naturally occurring tumors in our companion animal population (i.e., dog and cat pet population).
Companion animals with naturally occurring tumors, although presently underutilized, have and should continue to provide an excellent opportunity to investigate many aspects of malignancy Cited by: In contrast, examples of naturally occurring lens tumors were found in cats, dogs, rabbits, and birds.
In the veterinary school database, % of feline intraocular and adnexal neoplasms (/) were designated as feline ocular posttraumatic sarcoma, a tumor previously demonstrated to Cited by: 3.
The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents is a single volume, comprehensive book sanctioned by the American College of Laboratory Animal Medicine (ACLAM), covering the rabbit, guinea pig, hamster, gerbil and other rodents often used in research.
This well-illustrated reference won a PROSE Award for Best Single Volume. Request PDF | 9. Dog Models of Naturally Occurring Cancer | This chapter highlights the unique traits that make dog models effective in the integration of biomedical genomics and translational.This is an excellent addition to this well established collection of volumes published for the Imperial Cancer Research Fund by the Oxford University Press.
Indeed the animal models are well chosen and written about in such a way that this volume should be mandatory reading for anybody engaged in retroviral or oncological research, whether at the bench, clinic or epidemiological desk.
Cancer is a disease of the genome, arising from DNA alterations that dysregulate gene structure or function. Unraveling the pathogenesis of cancer has not only helped to understand how a cell transforms into a tumor but has also promoted molecular tests that now help diagnose and provide prognoses for a variety of cancers in humans and by: 2.