3 edition of Improving care for patients with malignant cerebral glioma found in the catalog.
Improving care for patients with malignant cerebral glioma
Includes bibliographical references.
|Statement||edited by Elizabeth Davies and Anthony Hopkins.|
|Contributions||Davies, Elizabeth, Hopkins, Anthony|
|LC Classifications||RC280.B7 I53 1997|
|The Physical Object|
|Number of Pages||123|
We present an analysis of end-of-life care for patients with malignant glioma as determined by analysis of SEER-Medicare data. Of the > patients included in this study, we found that over 60% enrolled in hospice before death, and the vast majority of those met length-of-stay landmarks of 3 and 7 days, which are associated with higher quality end-of-life care. Surgery is usually done to make a diagnosis and to improve symptoms, and it may be enough to cure benign tumors. Radiation therapy is required to treat gliomas. Radiation therapy may also be beneficial in the short-term for tumors that have spread from other parts of the body. Chemotherapy also benefits some patients with such tumors.
Neurosurg Clin North Am ;7(3) Meyers CA, Scheibel RS. Early detection and diagnosis of neurobehavioral disorders associated with cancer and its treatment. Oncology (Williston Park) ; Davies E, Clarke C, Hopkins ant cerebral glioma I: survival, disability, and morbidity after radiotherapy. BMJ ; This paper discusses the arguments for and against radical tumor resection as a strategy for treatment of cerebral gliomas. METHOD: Data from the Glioma Outcome Project were analyzed to determine whether survival could be related to extent of resection in patients treated by biopsy or resection for malignant cerebral gliomas. FINDINGS: Consistent survival advantages were noted for those.
During they affected individuals. 1 Around 85% of malignant brain tumors are classified as gliomas, and despite aggressive treatment by surgical resection, radiotherapy, and chemotherapy, only 40% of UK patients with brain cancer survive 1 year from diagnosis and only 19% survive 5 years. 2 The profound physical and cognitive effects. With the goal of seeking new knowledge and improving the reliability, comfort and cost of care, Mayo Clinic doctors continually study new diagnostic and treatment options through clinical trials. At Mayo Clinic, scientists and medical researchers are investigating the causes of gliomas and other brain tumors and aggressively developing new.
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QI principles were used by a multidisciplinary team to improve the quality of care for patients with glioma during the perioperative period.
Leadership involvement, ongoing dialogue across departments, and reporting of system performance were important for sustaining process by: 7.
Oppor tunities for improving the quality of care in malignant cerebral glioma There is scope for improving the ser vices o V ered to patients with malignant glioma. High-grade gliomas are incurable and long-term survival remains limited.
While low-grade glioma patients have better outcomes, their quality of life is often affected by a variety of symptoms as well. Helping glioma patients improve quality of life at all stages of illness is an important goal for the interdisciplinary care by: Book November The studies in this thesis focus on treatment of patients with malignant gliomas grade III and.
The aim of the studies is to improve the care of glioma patients. Malignant cerebral glioma. Patients should be treated in specialist units. Improving care for patients with malignant cerebral glioma. London: RCP Publications, 4 Brown GW, Har ris TO.
Clinical audit has highlighted several important issues including some variation in the management of patients aged o1 delays in beginning treatment, and problems with communication between different departments involved in patient care.2 A multidisciplinary Working Group, funded by the NHS Executive, recently developed evidence based guidelines for the management of these patients Cited by: 4.
Seizure prevalence during the last weeks of life is common with gliomas, occurring in 36% to 56% of patients,3, 5, 9, 12, 16 usually with an increase in frequency during the last month of life. 12 For example, an Italian study team 18 reported on patients who died at home and found % of their patients presented with one or more seizures.
The first phase II study by Vredenburgh et al. showed that bevacizumab and irinotecan given to patients with recurrent malignant gliomas, showed a 6-month progression-free survival (PFS) of 38%, 30% for those patients with GBM. The radiographic response rate was 1 patient with complete response and 19 patients with partial response (>50% decrease in tumor cross section).
MALIGNANT GLIOMAS 5 Malignant Gliomas: A Case Study The purpose of this paper is to describe and illustrate the clinical implications of malignant gliomas *. Although certain protocols regarding diagnosis, initial treatment, and progression are well characterized in the glioma literature, every cancer and patient are unique.
Introduction. Malignant glioma is the most common primary brain tumour in adults. It generally presents with epilepsy, cognitive change, headache, dysphasia, or progressive hemiparesis.1 Diagnosis is usually achieved by appropriate imaging studies (figs 1 and 2) followed by biopsy or surgery.2 3 A randomised trial shows that the median survival after surgery for patients on steroids alone is.
Elizabeth Davies and colleagues studied patients with high grade glioma from centres without dedicated neuro-oncology units,1 and their results provide a good argument for a reorganisation of cancer services to improve cancer care, in which specialist units provide not only state of the art treatment but also, and more importantly, a package of care and support.
Gliomas are primary brain tumors derived from cells of the glial (astrocytic and/or oligodendroglial) lineage. Gliomas are the most common childhood tumor of the central nervous system, accounting for 53% of tumors in children aged 0–14 years and 37% in adolescents aged 15 to 19 years. 1,2 As per the World Health Organization (WHO) classification system, these tumors are separated into low.
These therapies for malignant brain tumors were discovered and developed by researchers at the Johns Hopkins Comprehensive Brain Tumor Center, and both of these treatments are now used nationwide.
Children with brain tumors need specialized approaches and care to accommodate their developing brains and bodies. Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ GroupCited by: 4.
The book reinterprets the role of the cerebrum and sub-cortex, leverages scientific advances to improve cytoreduction and reduce neurological deficits, and challenges the myth of the "inoperable" glioma.
This is the first step-by-step technical guide focused on aggressively resecting different types of gliomas. This new edition guides you through the latest developments in the field, including hot topics like malignant gliomas, functional brain mapping, neurogenetics and the molecular biology of brain tumors, and biologic and gene therapy.
Glioma is the most common intracranial primary malignancy, with limited treatment options and a poor overall survival (OS). Immunotherapy has been used successfully in various cancers, leading to.
Davies E, Hopkins A. Improving care for patients with malignant cerebral glioma, London (UK): Royal College of Physicians of London; 2. Chang SM, Parney IF, Huang W, et al.
Patterns of care for adults with newly diagnosed malignant glioma. Over the past decade there has been considerable improvement in outcomes for patients with glioma. There has been a growing interest in research to increase survival and improve patients’ experience.
There is now high-quality evidence from many clinical trials of brain tumour treatments and supportive care. Gliomas are classified into four grades (I, II, III, and IV), and the treatment and prognosis depend upon the tumor grade. Grade I or II tumors are termed low-grade gliomas.
The term malignant or high-grade glioma refers to tumors that are classified as: Grade III (anaplastic astrocytoma, anaplastic oligodendroglioma, anaplastic ependymoma). High-grade glioma (HGG) is the most malignant type of brain tumour (BT) occurring most frequently in people aged 45– 1 Treated with optimal therapy, the median survival is 12–15 months with a 5-year survival of 10%.
2 Patients with HGG experience a high symptom burden related to the disease and the surgical procedures and medical treatments. 3 4 Different types of cerebral symptoms Cited by: Should patients with imaging suggestive of low grade glioma (LGG) undergo observation versus treatment involving a surgical procedure?
These recommendations apply to adults with imaging suggestive of a WHO grade 2 glioma (oligodendroglioma, astrocytoma, or oligo-astrocytoma).
Surgical resection is recommended over observation to improve overall survival for patients with diffuse low .Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy. Book • 2nd Edition • in part due to the lack of a proper control group in the first studies evaluating bevacizumab in malignant glioma patients, we have failed to prove a survival advantage for bevacizumab in this patient population.